Dr. Dennis Selkoe
- 430 Publications
Dr. Dennis Selkoe’s enduring efforts to learn more about Alzheimer’s disease began in medical school, where he discovered a love for biochemical laboratory work relating to cognitive impairment in the elderly.
As the Vincent and Stella Coates Professor of Neurologic Diseases in
Harvard Medical School and the Co-director of the Center for Neurologic Diseases in Brigham and Women’s Hospital, Dr. Selkoe has made great strides in uncovering the molecular pathology of the disease. He has received the Mathilde Solowey Award in the Neurosciences from the National Institute of Health, the Potamkin Prize from the American Academy of Neurology and the Lifetime Achievement Award from the Alzheimer’s Association in recognition of his contributions.
“I'd like to focus on exactly how the amyloid beta protein first binds to cells and injures them. We don't know how that happens. We know, with all this genetic and biomarker and pathology evidence briefly alluded to above, that amyloid beta protein builds up as you get Alzheimer's, but we don't know exactly how it short-circuits the nerve cells. We have some very exciting experiments underway to figure that out.”
-Dr/ Dennis Selkoe