Matching a Trial

There are many criteria for matching a specific clinical trial. Two important categories are:

  1. Current and Past Medications
    Current and past medications are important because each trial is looking for a specific type of patient. For example, a trial that is assessing an research drug for moderate to severe Crohn’s disease will likely want patients that have been on corticosteroids (e.g. prednisone) in the past because that indicates their disease was severe enough to require corticosteroids. Many trials these days are looking for patients that have been on a biologic (e.g. infliximab) in the past because those trials are investigating drugs for people that have failed a biologic and therefore don’t have many options left.
  2. Disease Activity
    Disease activity refers to whether or not someone is in remission or whether they have active disease (i.e. flaring). Most trials are looking for people who are flaring because main goal of those trials is often to see how well the research drug works for people. In other words, how effective and how safe is the research drug.

Other important criteria for matching trials are:

  • Whether or not you’ve had intestinal surgery. Many trials for Crohn’s or ulcerative colitis are looking for people who have not had intestinal surgery.
  • When you were diagnosed. Many trials for Crohn’s or ulcerative colitis are looking for people who were diagnosed at least 6 months ago.

There are dozens of criteria for determining the types of patients that clinical trials are looking for. The ones listed above are not a complete list by any means, however they do however highlight ones that distinguish one trial from another.


What You Need To Do

The Important Takeaway:  Update your profile answers if any of them change.

This is very important for our system to see if any current trials or upcoming trials match you. This will help you know your options.