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Should I be concerned about taking a biologic for ulcerative colitis?

Dr Brian Bressler


Ulcerative colitis is potentially a very serious disease and what we want to avoid is surgery, because it is the highest risk manoeuvre in treating a patient with ulcerative colitis. There is about a 2.5% risk of dying from that operation. There are no medications that we use that come close to that particular risk...

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Related Emerging Treatments

Limited to 800 Patients

Etrolizumab for Ulcerative Colitis (For patients who have previously used anti-TNFs)

Roche
Dr. Brian Bressler Dr. Brian Bressler

This study is evaluating how safe and effective etrolizumab is compared to placebo for the treatment of moderate to severe ulcerative colitis. Participants must have failed an anti-TNF therapy (e.g. Remicade, Humira, etc.) previously.
Limited to 200 Patients

Vedolizumab for Pouchitis

Takeda pharmaceutical company
Dr. Brian Bressler Dr. Brian Bressler

Vedolizumab is an intraveneous medication for ulcerative colitis who have had bowel surgery involving a proctocolectomy and ileal pouch anal anastomosis.
Limited to 350 Patients

Etrolizumab for Ulcerative Colitis (TNF Inhibitors Naive)

Roche
Dr. Brian Bressler Dr. Brian Bressler

This study is evaluating how safe and effective etrolizumab is compared to placebo for the treatment of moderate to severe ulcerative colitis. Participants must have not tried an anti-TNF therapy (e.g. Remicade, Humira, etc.).

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